Download Antitumor Steroids by R T Blickenstaff PDF

By R T Blickenstaff

Antitumor Steroids examines using steroids, besides nonsteroidal antiestrogens and a few benzo[a]carbazoles, within the therapy of melanoma. It explains the mechanism through which steroids and their receptors interact to impact their physiological capabilities mostly and their antitumor task particularly. It additionally describes the systematic screening of antitumor compounds remoted from typical resources.
Organized into 9 chapters, this ebook starts with an summary of the position of steroids in melanoma remedy. It then discusses the estrogens, antiestrogens, and compounds (all containing an fragrant A-ring). the following chapters give some thought to androgens, a few antiandrogens, derivatives in response to C-19 steroids, progestins and corticoids, bile acids, and compounds with a side-chain carboxyl staff. The ebook explains the biogenesis and metabolism of androgens; the pharmacology of medroxyprogesterone acetate; the antitumor homes of clearly happening corticosteroids; sterols and cucurbitacins; diet D and its metabolites; and cardenolides, bufadienolides, and withanolides. The booklet concludes with a bankruptcy on bile acids, sapogenins and its analogs, and miscellaneous steroids.
This ebook is a priceless source for natural and medicinal chemists biochemists, and pharmacologists attracted to using steroids in treating cancer.

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